Skip navigationThe Wellcome Trust Advanced Courses and Scientific Conferences

Questions or Queries

+44 (0) 1223 495100




Travel Information

Abstract Guidelines

Venue Details

Past Conferences

Sponsorship Opportunities

Terms and Conditions


Alzheimer's Disease in Down Syndrome: From molecules to cognition
27-29 March 2014

Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

This conference has now sold out - WAITLIST AVAILABLE

This new Wellcome Trust conference will focus on understanding the links between Down syndrome and Alzheimer's disease. With the Down syndrome population now approaching eight million, it is important to understand the nature and cause of the AD-like dementia that can occur in this disease. Our aim is to understand dementia in Down syndrome at the neurological, cognitive, behavioural, cellular and genetic levels, which will also inform our general understanding of Alzheimer's disease.

This multi-disciplinary meeting will focus on the development of biomarkers for early diagnosis of dementia in Down syndrome, the biochemical and cellular characteristics that differentiate those who will develop dementia from those who are protected, the genetics of behavioural and cognitive phenotypes seen in Alzheimer's disease and Down syndrome, and stem cell approaches to therapies for dementia. Panel discussions will be arranged on research collaborations and funding opportunities in these disease areas.

The meeting is aimed at clinicians, geneticists, neuroscientists and psychologists with an interest in Down syndrome and/or Alzheimer's disease. We welcome abstracts from all areas relevant to furthering our understanding of dementia in these diseases. Several oral presentations will be chosen from the abstracts submitted.

Scientific sessions
Clinical studies in Alzheimer's disease and Down syndrome
Developmental studies in Down syndrome: early markers for Alzheimer's disease?
Animal models
Cell modelling in dementia
Genetics and informatics

Scientific organising committee
Elizabeth Fisher University College London, UK
John Hardy University College London, UK
Annette Karmiloff-Smith Birkbeck, University of London, UK
Dean Nizetic Queen Mary, University of London, UK
Andre Strydom University College London, UKz
Victor Tybulewicz National Institute for Medical Research, UK
Frances Wiseman University College London, UK

Keynote speaker
Bill Mobley University of California San Diego, USA

Confirmed speakers
Jorge Busciglio University of California-Irvine, USA
Noel Buckley King's College London, UK
Antonia Coppus Radboud University Medical Centre, The Netherlands
Jamie Edgin University of Arizona, USA
Tony Holland University of Cambridge, UK
Annette Karmiloff-Smith Birkbeck, University of London, UK
Eric Karran Alzheimer's Research UK, UK
Omar Khwaja  F. Hoffmann-La Roche AG, Switzerland
Jeanne Lawrence University of Massachusetts Medical School, USA
Joseph Lee Columbia University, USA
Rick Livesey University of Cambridge, UK
Carolyn Mervis University of Louisville, USA
Derek Moore, University of East London, UK
Ralph Nixon NYU Langone Medical Center, USA
Dean Nizetic Queen Mary, University of London, UK
Jorge Palop University of California San Francisco, USA
Amy Pooler King's College London, UK
Jee Hoon Roh Asan Medical Center, South Korea
Anne Rovelet-Lecrux Inserm U1079, France
Nicole Schupf Columbia University Medical Center, USA
Frances Wiseman University College London, UK

Conference programme:
The conference will start at approximately 09.30 on Thursday, 27 March and close at approximately 13.15 on Saturday 28 March 2014.
A draft copy of the programme is now available.

Registration and Accommodation

Please note:
This conference has reached full capacity. At this time we are accepting waitlist requests. If you would like to join the waitlist please e-mail
Payment will not be requested at this time.

Registration and Accommodation
The standard accommodation packages include registration, meals and housing for the nights of the 27 & 28 March 2014.
The no accommodation package includes registration and meals only. 

Pre-conference accommodation & dinner on 26th March 2014
Has now sold out.

Has now sold out.

Has now sold out

Have now sold out

Abstracts and Posters

Poster boards onsite will accommodate 118 cm high by 84 cm wide (A0) of printed material. Accepted abstracts will appear in the conference programme book and poster boards will be allocated at the conference.

We are pround to announce that one of our sponsors, F1000, will be offering a poster prize that includes a F1000 certificate, a personal subscription to F1000Prime for a year (worth $125) and a free article submission to their open access journal F1000Research.

Wellcome Trust bursaries are not available for this conference; however, bursaries are available from The Biochemical Society.

For further information, please contact the conference organiser:
Emily Rees
Directdial: +44 (0) 1223 495111
Fax: +44 (0) 1223 495131


We would like to acknowledge the generous support from the following organisations (for information on sponsoring this conference, please contact us):



 Gibbs Building, 215 Euston Road, London NW1 2BE, UK   tel:+44 (0)20 7611 8888