A decade ago President Bill Clinton declared the draft sequence of the human genome "the most wondrous map ever produced by humankind". The promise of bringing genomics into the clinic is just now beginning to be realized, but in addition to the technological advancements required to fulfill that promise there is a need for training opportunities for interested clinicians.
This exciting new workshop will provide clinicians with an introduction to the field of complex disease genetics and its progress in recent years, including the success of genome-wide association studies, new biological insights and the transformative potential of next-generation sequencing technology. The course will combine lecture material from experts at the Wellcome Trust Genome Campus, computer-based practical sessions, and invited speakers from off-campus.
The recent advances of genetics and genomics are already affecting fields ranging from clinical genetics to cancer pathology, and will rapidly move across nearly all aspects of health care. The material presented here will help prepare clinicians for that coming change.
Target audience & prerequisites
The workshop is aimed at actively practicing clinicians (either general practitioners or hospital specialists) with an interest in the genetics of complex diseases, personal genomics or translation of genomics into clinical practice. Research-active clinicians are welcome, but this is not a requirement. Familiarity with basic genetic concepts (DNA, chromosomes, inheritance, etc) is expected, but core principles will be reviewed.
Please note: Places on the workshop will be limited to optimise practical sessions, discussions and access to instructors and speakers. Places will be awarded on merit and applicants must complete an application form when registering.
This workshop has been CPD approved by the Royal College of Physicians (12 credits).
Introduction to genetics & basic concepts
Methods for studying complex disease genetics: linkage, Genome-wide Association Studies (GWAS)
Missing heritability and next-generation sequencing
Direct to consumer testing
Emerging challenges in clinical genetics
Biological insights (pharmacogenetics, cancer, metabolic disease, immune disease)
Practical sessions (how to read GWAS papers, how to interpret a patientís genome)
Dr Jeff Barrett Group Leader Wellcome Trust Sanger Institute, Hinxton, UK
Dr Charlie Lees Consultant Gastroenterologist, Edinburgh, UK
Confirmed guest speakers
Mark McCarthy University of Oxford, UK
Daniel MacArthur Wellcome Trust Sanger Institute, Hinxton, UK
Helen Firth University of Cambridge, UK
Andrew Hattersley Peninsula College of Medicine & Dentistry, UK
Ultan McDermott Wellcome Trust Sanger Institute, Hinxton, UK
Registration fee and accommodation
The workshop is subsidised by the Wellcome Trust and there is a fee of £250 for clinical applicants. This covers course attendance, on-site accommodation for the night of Thursday 26 January 2012, meals and refreshments.
Please note: Registration is now closed. Click here to link to the 2013 course page.
If you would like any further information on the workshop or have have questions regarding the application process, please contact Laura Hubbard firstname.lastname@example.org.