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  Perspectives in Clinical Proteomics Conference 2012
14-15 March 2012
Wellcome Trust Conference Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

Registration is closed

Supprted by:

Perspectives in Clinical Proteomics is part of a series of open registration proteomics training workshops and a 2-day conference jointly sponsored by the Wellcome Trust and the European Bioinformatics Institute (EBI).

Following our successful meeting in 2010 where a broad range of stakeholders in the field were brought together to discuss the challenges and opportunities in the field of clinical proteomics, the Wellcome Trust and EBI are holding a follow-up meeting in March 2012. Reports and papers from that first meeting were published in Proteomics: Clinical Applications and Expert Reviews Proteomics. To enhance the insight into the translation of biomarkers into clinical practice that participants of the meeting will obtain, the meeting is drawing upon the expertise of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) and the American Association for Clinical Chemistry (AACC) through our scientific programme committee.

The 2012 conference will focus on the attributes of successful biomarker translation, aspects of emerging quantitative biomarker assays in the clinical chemistry laboratory, as well as in vitro diagnostic development and regulatory considerations.

Scientific Organising Committee:
Rolf Apweiler, European Bioinformatics Institute, UK
Roz Banks, University of Leeds, UK
Graham Beastall, IFCC, UK
Mike Dunn, UCD Conway Institute of Biomolecular and Biomedical Research, Ireland
Greg Miller, AACC, USA
Scott Patterson, Amgen Inc., USA
Cathie Sturgeon, University of Edinburgh, UK
Jennifer Van Eyk, Johns Hopkins University, USA

Speakers include:
Leigh Anderson, Plasma Proteome Institute, USA
Joan Bathon, Columbia Medical School, USA
Prasad Devarajan, Cincinnati Children's Hospital Medical Center, USA
Bruno Domon, Luxembourg Clinical Proteomics, Luxembourg
Alberto Gutierrez, FDA, USA
Jorg Hoheisel, DKFZ, Germany
Louise Jones, CRUK, UK
Jon Klein, University of Louisville, USA
John Lamont, Randox Laboratories Ltd, UK
Greg Miller, AACC, USA
Xavier Nassif,Faculté Paris Descartes/Necker, France
Adrian Newland, NICE, UK
Scott Patterson, Amgen Inc., USA
Chris Price, University of Oxford, UK
Emanuel Schwarz, University of Cambridge, UK
James Snider, Critical Diagnostics, USA
Allen Everett, Johns Hopkins University, USA

Conference Programme:

Please click here to download the full programme

Wednesday, 14 March

12.00 – 13.00   Registration & Lunch
13.00 – 13.15   Opening remarks

13.15 – 15.15 Session 1 Emerging Markers

13.15  Application of Proteomics to Understanding Chronic Kidney Disease and its Complications
          Jon Klein, University of Louisville, USA

13.45  Brain injury biomarkers in children: Discovery and translation into clinical care
          Allen Everett, Johns Hopkins University, USA

14.15  Evaluation of a Candidate Response Biomarker in Oncology: Challenges Extrapolating from Early Phase Studies
          Scott Patterson, Amgen Inc., USA

14.45  Cardiovascular Complications of Rheumatoid Arthritis:  multiple strategies for biomarker development.”
          Joan Bathon, Columbia Medical School, USA

15.15 – 15.45  Afternoon tea

15.45 – 17.45  Session 2 Quantitative Assays

15.45  Quantification of Biomarker Candidates in Bodily Fluids Using High Resolution Tandem Mass Spectrometry
          Bruno Domon, Luxembourg Clinical Proteomics, Luxembourg

16.15  Biomarker Discovery for Complex Disorders: A Schizophrenia Case Study
          Emanuel Schwarz, Cambridge University, UK

16.45  Affinity-based proteomic analysis of pancreatic cancer
          Jorg Hoheisel, DKFZ, Germany

17.15 – 19.00  Poster Session with drinks reception

19.00   Conference Dinner

Thursday, 15 March

09.00 – 11.00  Session 3 Diagnostic Development

09.00  Experience of a diagnostic manufacturer in the translation of biomarkers into clinical use
          John Lamont, Randox, UK

09.30  Found in Translation, Taking The Cardiac Biomarker ST2 from Discovery to Clinical Validation
          James Snider, Critical Diagnostics, USA

10.00  Acute Kidney Injury Biomarkers - Bench to Bedside
          Prasad Devarajan, Cincinnati Children's Hospital Medical Center, USA

10.30  Use of Mass Spectrometry for Bacterial Identification in the Clinical Laboratory
          Xavier Nassif, Faculté Paris Descartes/Necker, France

11.00 – 11.30  Morning coffee

11.30 – 13.00  Session 4 Regulatory Impact

11.30  Title tbc
          Alberto Gutierrez, FDA, USA

12.00  Title tbc
          EMEA, Belgium

12.30  Diagnostic Interventions reviewed by HTA: the NICE Diagnostics Assessment Programme
          Adrian Newland, NICE, UK

13.00 – 14.00  Lunch

14.00 – 15.30  Session 5 Biomarkers into practice in the Clinical Laboratory

14.00 From chaos to order: harmonization of clinical laboratory test results
         Greg Miller, AACC, USA

14.30  Title tbc
          Ian Young, IFCC, UK
15.00  Barriers to Adoption of New Biomarkers
          Chris Price, University of Oxford, UK

15.30 – 16.00  Afternoon tea

16.00 – 17.00  Session 6 Enabling Translation

16.00  Addressing the Clinical Proteome with Mass Spectrometric Assays 
          Leigh Anderson, Plasma Proteome Institute, USA

16.30  Translational Research and Stratified Medicine… New opportunities, new horizons - a funders perspective
          Louise Jones, CRUK ,UK

17.00   Closing remarks

17.15   Coaches depart for Cambridge and Stansted & Heathrow airports

Related workshops
Delegates may also be interested in the following related workshop provided by the Wellcome Trust and EBI: 

Perspectives in Clinical Proteomics Training Workshop, 15 - 17 March 2012. Click here for details.

Registration and Accommodation

Student No Accommodation      £150.00
Student  Twin Accommodation  £197.00
Student Single Accommodation   £228.00
Academic No Accommodation  £250.00
Academic Twin Accommodation  £297.00
Academic Single Accommodation  £328.00
Commercial No Accommodation   £350.00
Commercial Twin Accommodation  £397.00
Commercial   Single Accommodation   £428.00

Registration is closed


The accommodation packages include registration, meals and housing for the night of Wednesday, 14 March 2012.  If you require additional nights this will be at an additional cost and subject to availability, please contact the conference centre at  directly for further information. 

The no accommodation packages include registration and meals only.

Important – limited on-site accommodation
As we have limited bedrooms on-site, bedrooms on the Hinxton campus will be allocated on a first come, first serve basis. Early registration is recommended. To view more information on the Wellcome Trust Conference Centre accommodation,
please click here

Once we have reached capacity on campus, delegates will be advised to make their own arrangements, please contact local hotel information.

Travel Visas

If you require a letter of acceptance in order to obtain a travel Visa please e-mail

Abstracts and Posters

Please ensure that you follow the abstract guidelines and upload your abstract during registration. If you are not ready to up-load you’re abstract at the time of registration, please e-mail your abstract document to no later than 1 February 2012.

Abstract Deadline is Wednesday, 1 February 2012

After the abstract deadline the scientific committee will assess your abstract and you will be notified whether you have been selected for a short talk or poster presentation.

Poster boards onsite will accommodate 118 cm high by 84 cm wide (A0- portrait) of printed material.  Accepted abstracts will appear in the conference programme book and poster boards will be allocated at the conference.



We would like to acknowledge the generous support from the following organisations:






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